Best Time to Take Creatine While Intermittent Fasting (Evidence Based)


Intermittent fasting (IF) has rapidly gained traction and has been praised for its potential to help with weight management, improve metabolic health, and even extend longevity.

At the same time, creatine—one of the most studied supplements in the fitness world—is celebrated for its ability to enhance athletic performance and support muscle growth.

Creatine supplementation has been shown to increase muscle mass by 1.0% to 2.3%, thanks largely to gains in fat-free mass and skeletal muscle. Due to this powerful effect, creatine is an important part of the routines of many athletes and exercise fans.

So, what happens when you combine these two practices? Is there an ideal time to take creatine while intermittent fasting? Can it break your fast, and does timing really matter?

Let’s dive into the science and clear up the confusion.

Creatine and Intermittent Fasting: Understanding the Relationship

Before we delve into the timing, let's first grasp how creatine and intermittent fasting interact within your body.

Creatine's Role

Creatine quickly replaces lost phosphate molecules to help ATP, the body's main energy source, be made again. According to the Journal of Muscle Research and Cell Motility, when you need extra power for intense activities like lifting or running. So, when you do short, intense workouts, your muscles can keep going longer and with more force.

Beyond its well-known role in muscle performance, emerging research suggests that creatine may offer additional benefits, particularly intriguing for those practicing intermittent fasting. Nutrition Reviews indicates that creatine might support cognitive function, potentially enhancing memory and focus - perfect for those early morning fasted workouts when mental clarity is key.

Additionally, a study by Medicine & Science in Sports & Exercise shows that creatine may play a role in bone health, an important consideration when navigating the potential impact of fasting on bone density. While more research is needed, these findings hint at creatine's multifaceted potential beyond just muscle gains.

Intermittent Fasting's Impact

Intermittent fasting puts your body in a fasted state for a certain period. During this time, your body shifts its energy source from glucose to stored fat, and cellular repair processes kick into high gear, as noted by Nature Reviews Neuroscience. This process has been shown to improve brain health and resilience.

Some people worry that taking creatine during a fast might interfere with these metabolic changes or even break the fast, thus negating its benefits.

Creatine is calorie-free and doesn't trigger a significant insulin response, a hormone that signals your body to switch from a fasted to a fed state. So, you can rest assured that your fast remains intact.

However, while creatine itself won't break your fast, the timing of its intake can influence its effectiveness and how your body utilizes it.

Evidence-Based Recommendations for Creatine Timing

Here are some of the best times to take creatine while intermittent fasting.

During Your Eating Window

The most straightforward and foolproof approach is to take creatine during your eating window. This keeps your fast unbroken and may help your body absorb it better if you take it with food.

  • Preserves Your Fast: Taking creatine during your eating window guarantees that you won't inadvertently consume any calories or trigger an insulin response that could disrupt your fast. This is especially crucial if you're aiming for specific metabolic benefits associated with fasting, such as autophagy or ketosis.
  • Improved Absorption Potential: Research by the American Physiological Society suggests that consuming creatine with food, particularly carbohydrates, may enhance its absorption and utilization by your muscles. This is because carbohydrates stimulate insulin release, which can help shuttle creatine into muscle cells more efficiently.

Timing Around Workouts

If your workout routine falls within your eating window, consider taking creatine shortly before or after your exercise session. The Journal of Strength and Conditioning Research suggests that this timing might enhance muscle uptake and potentially lead to better performance gains.

Studies from the Journal of the International Society of Sports Nutrition have shown that post-workout creatine intake might be slightly more beneficial for muscle growth, but the difference is likely minimal. It's important to take it close to your workout, whether it's before or after.

With Carbohydrates

Pairing creatine with carbohydrates is beneficial for better absorption. Consuming carbohydrates raises insulin levels, which in turn makes it easier for creatine to get into muscle cells.

Aim for easily digestible carbs like fruits, rice, or potatoes. These provide a quick source of glucose, triggering insulin release, which acts as a shuttle for creatine into your muscles.

During the Fasting Window (If Necessary)

Sometimes, your workout schedule or personal preferences might necessitate taking creatine during your fasting window. If that's the case, don't worry; there are options:

  • With Non-Caloric Fluids: If your workout falls during your fasting window, mix it with plain water or other calorie-free beverages like black coffee or unsweetened tea. These options provide a convenient way to consume creatine without significantly impacting your fasted state or triggering an insulin response.

  • Pure Creatine Monohydrate: Choosing pure creatine monohydrate powder is the simplest and safest option. Make sure it's unflavored and has no added sweeteners or other ingredients. This guarantees you're getting pure creatine and nothing else that could potentially break your fast.

While research on creatine timing during fasting is still evolving, these approaches are considered safe and effective. They allow you to maintain your fast while potentially reaping the benefits of creatine supplementation.

Key Points to Remember

Learn how to prepare and use creatine properly. In this guide, we’ll cover why you can skip the loading phase and just focus on a steady daily dose. Besides timing, there are other important factors to consider. We’ll also discuss how to adjust your intake to meet your specific goals.

No Loading Phase Required

It’s okay to skip traditional creatine loading protocols. Research shows that a consistent daily dose of 5-7 grams is enough to saturate your muscles over time.

This is especially beneficial for those following intermittent fasting, as it simplifies the supplementation process and eliminates the need for large, calorie-dense loading doses.

Hydration is Crucial

Creatine acts like a sponge, drawing water into your muscle cells. Increasing cell volume and promoting muscle growth are key benefits.

However, the Journal of Athletic Training emphasizes that staying adequately hydrated is crucial, especially during intermittent fasting when you're already prone to fluid loss. Dehydration can not only hinder creatine's effectiveness but also negatively impact your overall performance and well-being.

Creatine Monohydrate is the Gold Standard

Creatine monohydrate is the most researched and widely available form of creatine. It's been proven effective and is generally the most affordable option.

While other forms of creatine exist, like creatine hydrochloride or creatine ethyl ester, they often come with a higher price tag and lack the same level of scientific backing.

Individual Needs Matter

General recommendations for creatine dosage and timing are a great starting point, but individual needs vary. Your fitness goals, training intensity, body composition, and even your dietary habits can all play a role in determining the best creatine plan for you. Listen to your body's signals and adjust as needed.

Maximize Creatine in Your Intermittent Fasting

When used correctly, intermittent fasting and creatine can complement one another well. Conventional loading phases are not required, however, maintaining daily intake consistency and enough hydration is essential for best outcomes.

As with any supplement, it's always wise to consult with a healthcare professional or registered dietitian before starting creatine, especially if you have any underlying health conditions or concerns.

They can provide personalized guidance based on your specific situation and goals. For its recognized benefits and affordable price, creatine monohydrate remains the best choice.

In the end, there isn't a strategy that works for everyone. Observe your body's reaction and modify your creatine intake to suit your particular fasting schedule and fitness objectives. By following these evidence-based recommendations and prioritizing consistency, you can safely and effectively incorporate creatine into your intermittent fasting routine.